Quinta pars o terrae incognitae?

Terrae Incognitae: Integrative Genomic Analysis of Hnrnp L Splicing Regulation

Alternative splicing is a critical component of human gene control that generates functional diversity from a limited genome. Defects in alternative splicing are associated with disease in humans. Alternative splicing is regulated developmentally and physiologically by the combinatorial actions of cisand trans-acting factors, including RNA binding proteins that regulate splicing through sequenc...

Emergência da quinta onda de inovação bancária

Chitinophaga terrae Bacteremia in Human

To the Editor: The genus Chitinophaga, first described by Sangkhobol and Skerman in 1981, belongs to the phylum Bacteroidetes (formerly the Cytophaga-Flexibacter-Bacteroides group), which includes filamentous, chitinolytic, gliding bacteria that transform into spherical bodies upon aging (1). This genus contains 10 environmental species that demonstrate similarities in 16S rDNA sequence and in ...

[Anemia in heart failure: pathophysiology, pathogenesis, treatment, and incognitae].

Although anemia now occupies an important place in our present understanding of the pathogenesis of heart failure, the condition is surrounded in mystery. Anemia is highly prevalent in patients with heart failure and is of great clinical significance. However, the treatment targets for anemia in patients with heart failure have still not been accurately defined. The present article reviews of t...

Geographies and Cartographies of Silence

Abstract. The earth’s inhabited areas are uneven in the knowledge about peoples, landscapes and activities. The unevenness is attributed to the collection and dissemination of place-based knowledge by colonial powers, countries with long traditions of print knowledge, including the production of maps, and also the production of electronic information. We explore the concepts of terrae incognita...